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Article

SSLPred: predicting synthetic sickness lethality.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2012

Bandyopadhyay Nirmalya, Ranka Sanjay, Kahveci Tamer

Abstract excerpt

Two genes in an organism have a Synthetic Sickness Lethality (SSL) interaction, if their joint deletion leads to a lower than expected fitness. Synthetic Gene Array (SGA) is a technique that helps in identifying SSL values for pairs of genes in a given set of genes. SSL interactions are useful to discover the co-expressed gene groups in the regulatory and signaling networks. Also, they are used to unravel the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22174258

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