Article
Externalization of saw-tooth architecture in small serrated polyps implies the presence of methylation of IGFBP7.
Digestive diseases and sciences - 1 May 2012
Kaji Eisuke, Uraoka Toshio, Kato Jun, Hiraoka Sakiko, Suzuki Hideyuki, Akita Mitsuhiro, Saito Shunsuke, Tanaka Takehiro, Ohara Nobuya, Yamamoto Kazuhide
Abstract excerpt
INTRODUCTION: Serrated polyps have been considered to be precursors of colorectal cancer with microsatellite instability. However, the biological and/or morphological changes which occur during the course of serrated polyp to cancer remain to be elucidated. METHODS: Twenty-eight colorectal serrated polyps including five mixed polyps (MP) from 20 patients were observed by chromoendoscopy with magnification, and...
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