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Article

The prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/ COX2) rs5277 polymorphism does not influence risk of colorectal cancer in an Iranian population.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014

Khorshidi Fatemeh, Haghighi Mahdi Montazer, Nazemalhosseini Mojarad Ehsan, Azimzadeh Pedram, Damavand Behzad, Vahedi Mohsen, Almasi Shohreh, Aghdaei Hamid Asadzadeh, Zali Mohammad Reza

Abstract excerpt

BACKGROUND: The prostaglandin-endoperoxide synthase 2 [PTGS2, commonly known as cyclooxygenase-2 (COX-2)] is an enzyme induced by proinflammatory stimuli that is often overexpressed in malignant tissue and involved in the synthesis of prostaglandins and thromboxanes, regulators of processes such as inflammation, cell proliferation, and angiogenesis, all relevant for cancer development. We investigated whether a...

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Identifiers

PMID: 24870748
DOI: 10.7314/apjcp.2014.15.8.3507

Genes

PTGS2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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