Article
Host genes and influenza pathogenesis in humans: an emerging paradigm.
Current opinion in virology - 1 Oct 2015
To Kelvin Kai-Wang, Zhou Jie, Chan Jasper Fuk-Woo, Yuen Kwok-Yung
Abstract excerpt
The emergence of the pandemic influenza virus A(H1N1)pdm09 in 2009 and avian influenza virus A(H7N9) in 2013 provided unique opportunities for assessing genetic predispositions to severe disease because many patients did not have any underlying risk factor or neutralizing antibody against these agents, in contrast to seasonal influenza viruses. High-throughput screening platforms and large human or animal...
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