Article
Major histocompatibility complex haplotype studies in Ashkenazi Jewish patients with pemphigus vulgaris.
Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 1990
Ahmed A R, Yunis E J, Khatri K, Wagner R, Notani G, Awdeh Z, Alper C A
Abstract excerpt
Of 26 Ashkenazi Jewish patients with pemphigus vulgaris, 24 (92.3%) carried the major histocompatibility complex (MHC) class II alleles HLA-DR4, DQw3, of which all were of the subtype DR4, DQw8. From studies of the patients and their families, haplotypes were defined. It was found that, of the patients who carried HLA-DR4, DQw8, 75% carried one or the other (and in one case, both) of two haplotypes [HLA-B38,...
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