HLA-H mutations in the Ashkenazi Jewish population.

doi:10.1006/bcmd.1997.0125

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Article

HLA-H mutations in the Ashkenazi Jewish population.

Blood cells, molecules & diseases - 1 Jan 1997

Beutler E, Gelbart T

Abstract excerpt

Hereditary hemochromatosis is a common disorder in people of European origin. The HLA-H gene has been found to have two mutations that apparently cause hemochromatosis. The principal mutation, 845G-->A (C282Y), is believed to have arisen relatively recently in the Celtic population. To determine...

Topics

Genotype
HLA Antigens
Hemochromatosis
Hemochromatosis Protein
Histocompatibility Antigens Class I
Humans
Jews
Membrane Proteins
Mutation
Sequence Analysis, DNA

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