Article
HLA-DRB1*04 and DRB1*14 alleles are associated with susceptibility to pemphigus among Japanese.
The Journal of investigative dermatology - 1 Nov 1997
Miyagawa S, Higashimine I, Iida T, Yamashina Y, Fukumoto T, Shirai T
Abstract excerpt
It has previously been demonstrated that susceptibility to pemphigus vulgaris is associated with human leukocyte antigen (HLA)-DR4 serologic specificity among Ashkenase Jews, and with DR4 as well as DR6 (DR14) in other ethnic groups. We genotyped HLA-DRB1, DQA1, DQB1, and DPB1 alleles in 16 patients with pemphigus by polymerase chain reaction-restriction fragment length polymorphism, to find evidence of potential...
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