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Article

Acquisition of resistance to avian leukosis virus subgroup B through mutations on tvb cysteine-rich domains in DF-1 chicken fibroblasts.

Veterinary research - 13 Sept 2017

Lee Hong Jo, Lee Kyung Youn, Park Young Hyun, Choi Hee Jung, Yao Yongxiu, Nair Venugopal, Han Jae Yong

Abstract excerpt

Avian leukosis virus (ALV) is a retrovirus that causes tumors in avian species, and its vertical and horizontal transmission in poultry flocks results in enormous economic losses. Despite the discovery of specific host receptors, there have been few reports on the modulation of viral susceptibility via genetic modification. We therefore engineered acquired resistance to ALV subgroup B using CRISPR/Cas9-mediated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28903753
DOI: 10.1186/s13567-017-0454-1
PMCID: PMC5598054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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