Article
Intronic deletions of tva receptor gene decrease the susceptibility to infection by avian sarcoma and leukosis virus subgroup A.
Scientific reports - 15 Apr 2015
Chen Weiguo, Liu Yang, Li Hongxing, Chang Shuang, Shu Dingming, Zhang Huanmin, Chen Feng, Xie Qingmei
Abstract excerpt
The group of avian sarcoma and leukosis virus (ASLV) in chickens contains six highly related subgroups, A to E and J. Four genetic loci, tva, tvb, tvc and tvj, encode for corresponding receptors that determine the susceptibility to the ASLV subgroups. The prevalence of ASLV in hosts may have imposed strong selection pressure toward resistance to ASLV infection, and the resistant alleles in all four receptor genes...
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