Article
Naturally Occurring Frameshift Mutations in the tvb Receptor Gene Are Responsible for Decreased Susceptibility of Chicken to Infection with Avian Leukosis Virus Subgroups B, D, and E.
Journal of virology - 15 Apr 2018
Li Xinjian, Chen Weiguo, Zhang Huanmin, Li Aijun, Shu Dingming, Li Hongxing, Dai Zhenkai, Yan Yiming, Zhang Xinheng, Lin Wencheng, Ma Jingyun, Xie Qingmei
Abstract excerpt
The group of highly related avian leukosis viruses (ALVs) in chickens are thought to have evolved from a common retroviral ancestor into six subgroups, A to E and J. These ALV subgroups use diverse cellular proteins encoded by four genetic loci in chickens as receptors to gain entry into host cells. Hosts exposed to ALVs might be under selective pressure to develop resistance to ALV infection. Indeed, resistance...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.