Article
Phenotype-related differences in the expression of D-type cyclins in human B cell-derived lines.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Dec 1996
Pokrovskaja K, Ehlin-Henriksson B, Bartkova J, Bartek J, Scuderi R, Szekely L, Wiman K G, Klein G
Abstract excerpt
Exposure of normal resting B lymphocytes to EBV in vitro leads to activation, subsequent immortalization, and the establishment of lymphoblastoid cell lines (LCLs). The endemic form of Burkitt's lymphoma (BL) is associated with EBV. EBV-positive BL lines maintain the original tumor phenotype (gro...
Topics
- B-Lymphocytes
- Blotting, Northern
- Blotting, Western
- Burkitt Lymphoma
- Cell Line
- Cyclin D2
- Cyclin D3
- Cyclins
- Flow Cytometry
- Gene Expression
- Herpesvirus 4, Human
