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Article

Promoter switching in Epstein-Barr virus during the initial stages of infection of B lymphocytes.

Proceedings of the National Academy of Sciences of the United States of America - 1 Mar 1990

Woisetschlaeger M, Yandava C N, Furmanski L A, Strominger J L, Speck S H

Abstract excerpt

Transcription of the genes encoding the six viral nuclear antigens present in Epstein-Barr virus latently infected lymphocytes can be initiated from one of two promoters (Cp and Wp) mapping near the left end of the viral genome. These promoters are used in a mutually exclusive manner in clonal cell lines established from either Burkitt lymphoma tumors or in vitro infection of peripheral B lymphocytes. In this...

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Identifiers

PMID: 2155423
DOI: 10.1073/pnas.87.5.1725
PMCID: PMC53555

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