Article
Antigenic Characterization of Human Monoclonal Antibodies for Therapeutic Use against H7N9 Avian Influenza Virus.
Journal of virology - 31 Jan 2023
Chang Pengxiang, Lukosaityte Deimante, Sealy Joshua E, Rijal Pramila, Sadeyen Jean-Remy, Bhat Sushant, Crossley Sylvia, Daines Rebecca, Huang Kuan-Yin A, Townsend Alain R, Iqbal Munir
Abstract excerpt
Since 2013, H7N9 avian influenza viruses (AIVs) have caused more than 1,500 human infections and the culling of millions of poultry. Despite large-scale poultry vaccination, H7N9 AIVs continue to circulate among poultry in China and pose a threat to human health. Previously, we isolated and generated four monoclonal antibodies (mAbs) derived from humans naturally infected with H7N9 AIV. Here, we investigated the...
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