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Article

Epidermal growth factor receptor protein expression and genomic alterations in renal cell carcinoma.

Cancer - 1 Mar 2012

Minner Sarah, Rump Dorothea, Tennstedt Pierre, Simon Ronald, Burandt Eike, Terracciano Luigi, Moch Holger, Wilczak Waldemar, Bokemeyer Carsten, Fisch Margit, Sauter Guido, Eichelberg Christian

Abstract excerpt

BACKGROUND: Epidermal growth factor receptor (EGFR) is involved in the progression of many cancer types and represents an important therapeutic target. METHODS: To determine the role of EGFR in renal cell carcinoma (RCC), the authors analyzed 1088 tumors in a tissue microarray format by using immunohistochemistry and fluorescence in situ hybridization (FISH). A subset of 63 cancers was sequenced for EGFR exon 18...

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Source

Identifiers

PMID: 22161775
DOI: 10.1002/cncr.26436

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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