Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease.

doi:10.1002/hep.23622

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Article

Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease.

Hepatology (Baltimore, Md.) - 1 Apr 2010

Valenti Luca, Al-Serri Ahmad, Daly Ann K, Galmozzi Enrico, Rametta Raffaela, Dongiovanni Paola, Nobili Valerio, Mozzi Enrico, Roviaro Giancarlo, Vanni Ester, Bugianesi Elisabetta, Maggioni Marco, Fracanzani Anna Ludovica, Fargion Silvia, Day Christopher P

Abstract excerpt

UNLABELLED: Inherited factors play a major role in the predisposition to nonalcoholic fatty liver disease (NAFLD), and the rs738409 C-->G polymorphism of PNPLA3/adiponutrin, encoding for the isoleucine-to-methionine substitution at residue 148 (I148M) protein variant, has recently been recognized...

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PMID: 20373368
DOI: 10.1002/hep.23622

Genes

PNPLA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20373368-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease.PMID 20373368Read ↗

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