Article
M(3): an improved SNP calling algorithm for Illumina BeadArray data.
Bioinformatics (Oxford, England) - 1 Feb 2012
Li Gengxin, Gelernter Joel, Kranzler Henry R, Zhao Hongyu
Abstract excerpt
SUMMARY: Genotype calling from high-throughput platforms such as Illumina and Affymetrix is a critical step in data processing, so that accurate information on genetic variants can be obtained for phenotype-genotype association studies. A number of algorithms have been developed to infer genotypes from data generated through the Illumina BeadStation platform, including GenCall, GenoSNP, Illuminus and CRLMM. Most...
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