Article
Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips.
BMC bioinformatics - 8 Mar 2011
Ritchie Matthew E, Liu Ruijie, Carvalho Benilton S, Irizarry Rafael A
Abstract excerpt
BACKGROUND: Illumina's Infinium SNP BeadChips are extensively used in both small and large-scale genetic studies. A fundamental step in any analysis is the processing of raw allele A and allele B intensities from each SNP into genotype calls (AA, AB, BB). Various algorithms which make use of different statistical models are available for this task. We compare four methods (GenCall, Illuminus, GenoSNP and CRLMM)...
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