Article
The joint allele frequency spectrum of multiple populations: a coalescent theory approach.
Theoretical population biology - 1 Mar 2012
Chen Hua
Abstract excerpt
The allele frequency spectrum is a series of statistics that describe genetic polymorphism, and is commonly used for inferring population genetic parameters and detecting natural selection. Population genetic theory on the allele frequency spectrum for a single population has been well studied using both coalescent theory and diffusion equations. Recently, the theory was extended to the joint allele frequency...
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