A non-zero variance of Tajima's estimator for two sequences even for infinitely many unlinked loci.

Abstract excerpt

The population-scaled mutation rate, θ, is informative on the effective population size and is thus widely used in population genetics. We show that for two sequences and n unlinked loci, the variance of Tajima's estimator (θˆ), which is the average number of pairwise differences, does not vanish even as n→∞. The non-zero variance of θˆ results from a (weak) correlation between coalescence times even at unlinked...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Computer Simulation
• Share to Demography
• Share to Genealogy and Heraldry