Article
Demographic inference using spectral methods on SNP data, with an analysis of the human out-of-Africa expansion.
Genetics - 1 Oct 2012
Lukic Sergio, Hey Jody
Abstract excerpt
We present an implementation of a recently introduced method for estimating the allele-frequency spectrum under the diffusion approximation. For single-nucleotide polymorphism (SNP) frequency data from multiple populations, the method computes numerical solutions to the allele-frequency spectrum (AFS) under a complex model that includes population splitting events, migration, population expansion, and admixture....
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