Article
Antimutagenic action of cobaltous chloride on radiation-induced mutations in cultured Chinese hamster cells.
Mutation research - 1 Oct 1990
Yokoiyama A, Kada T, Kuroda Y
Abstract excerpt
The effects of cobaltous chloride on 8-azaguanine (8AG)-resistant mutations induced by gamma-rays or ultraviolet (UV) light in cultured Chinese hamster V79 cells were examined. Cobaltous chloride alone had no significant effects on survival and mutations of V79 cells at concentrations less than 1 x 10(-5) M. Cobaltous chloride at a concentration of 3 x 10(-6) M had a marked effect in reducing 8AG-resistant...
Topics
- Animals
- Azaguanine
- Cell Line
- Cell Survival
- Cobalt
- Cricetinae
- Cricetulus
- Dose-Response Relationship, Radiation
- Gamma Rays
- Lung
- Mutagens
- Mutation