Article
Possible carcinogenic effects of X-rays in a transgenerational study with CBA mice.
Carcinogenesis - 1 Feb 1999
Mohr U, Dasenbrock C, Tillmann T, Kohler M, Kamino K, Hagemann G, Morawietz G, Campo E, Cazorla M, Fernandez P, Hernandez L, Cardesa A, Tomatis L
Abstract excerpt
A lifetime experiment using 4279 CBA/J mice was carried out to investigate whether the pre-conceptual exposure of sperm cells to X-ray radiation or urethane would result in an increased cancer risk in the untreated progeny, and/or increased susceptibility to cancer following exposure to a promoting agent. The study consisted of four main groups, namely a control group (saline), a urethane group (1 mg/g body wt)...
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