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Article

Streptococcus pneumoniae pep27 mutant as a live vaccine for serotype-independent protection in mice.

Vaccine - 2 Mar 2012

Kim Eun-Hye, Choi Sang-Yoon, Kwon Min-Kyoung, Tran Thao Dang-Hien, Park Sang-Sang, Lee Kwang-Jun, Bae Song-Mee, Briles David E, Rhee Dong-Kwon

Abstract excerpt

Streptococcus pneumoniae (pneumococcus) is responsible for significant morbidity and mortality in worldwide. After introduction of current pneumococcal vaccines, a marked decrease in the incidence of pneumococcal disease was observed. Unfortunately, serotype shifts in carriage and disease, including capsular switch and presence of antimicrobial resistance, have been found. Here we report live attenuated vaccine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22154770
DOI: 10.1016/j.vaccine.2011.11.073

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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