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Article

Rapid killing of Streptococcus pneumoniae with a bacteriophage cell wall hydrolase.

Science (New York, N.Y.) - 7 Dec 2001

Loeffler J M, Nelson D, Fischetti V A

Abstract excerpt

Nasopharyngeal carriage is the major reservoir for Streptococcus pneumoniae in the community. Although eliminating this reservoir would greatly reduce disease occurrence, no suitable intervention has been available for this purpose. We show here that seconds after contact, a purified pneumococcal bacteriophage lytic enzyme (Pal) is able to kill 15 common serotypes of pneumococci, including highly...

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Identifiers

PMID: 11739958
DOI: 10.1126/science.1066869

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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