Article
Intranasal Immunization With an Attenuated pep27 Mutant Provides Protection From Influenza Virus and Secondary Pneumococcal Infections.
The Journal of infectious diseases - 30 Jan 2018
Seon Seung Han, Choi Jung Ah, Yang Eunji, Pyo Sukneung, Song Man Ki, Rhee Dong-Kwon
Abstract excerpt
During influenza pandemics, secondary pneumococcal infections cause excessive mortality. However, the current 13-valent pneumococcal conjugate vaccine, PCV13, provides only limited protection against secondary infection. Therefore, a more effective pneumococcal vaccine is required to protect against secondary pneumococcal infections. Here, intranasal immunization with an attenuated pneumococcal pep27 mutant...
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