Article
Genetic variability in IL23R and risk of colorectal adenoma and colorectal cancer.
Cancer epidemiology - 1 Apr 2012
Poole Elizabeth M, Curtin Karen, Hsu Li, Duggan David J, Makar Karen W, Xiao Liren, Carlson Christopher S, Caan Bette J, Potter John D, Slattery Martha L, Ulrich Cornelia M
Abstract excerpt
Inflammatory processes, including, specifically, the inflammatory conditions Crohn's disease (CD) and ulcerative colitis (UC) predispose to colorectal cancer. Interleukin-23 is involved in pro-inflammatory signaling; genetic variation in the interleukin-23 receptor (IL23R) has been consistently a...
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