Article
Rapid forward-in-time simulation at the chromosome and genome level.
BMC bioinformatics - 9 Jul 2013
Aberer Andre J, Stamatakis Alexandros
Abstract excerpt
BACKGROUND: In population genetics, simulation is a fundamental tool for analyzing how basic evolutionary forces such as natural selection, recombination, and mutation shape the genetic landscape of a population. Forward simulation represents the most powerful, but, at the same time, most compute-intensive approach for simulating the genetic material of a population. RESULTS: We introduce AnA-FiTS, a highly...
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