Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study.

doi:10.1093/cid/cir827

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Article

Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Feb 2012

Johnson Melissa D, Plantinga Theo S, van de Vosse Esther, Velez Edwards Digna R, Smith P Brian, Alexander Barbara D, Yang John C, Kremer Dennis, Laird Gregory M, Oosting Marije, Joosten Leo A B, van der Meer Jos W M, van Dissel Jaap T, Walsh Thomas J, Perfect John R, Kullberg Bart-Jan, Scott William K, Netea Mihai G

Abstract excerpt

BACKGROUND: Candida bloodstream infections cause significant morbidity and mortality among hospitalized patients. Although clinical and microbiological factors affecting prognosis have been identified, the impact of genetic variation in the innate immune responses mediated by cytokines on outcomes of infection remains to be studied. METHODS: A cohort of 338 candidemia patients and 351 noninfected controls were...

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PMID: 22144535
DOI: 10.1093/cid/cir827
PMCID: PMC3269308

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IFNG

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Source receipt: pubmed, retrieved 7 Sept 2026.

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