Article
Cytokine and cytokine receptor polymorphisms in infectious disease.
Intensive care medicine - 1 Jan 2000
van Deventer S J
Abstract excerpt
Host immune responses strongly control the outcome of infectious disease, and the resistance to bacterial infections in humans is in part genetically determined. Responses to Gram-negative bacterial endotoxin are affected by the concentration of plasma lipoproteins and lipid transport proteins that are genetically controlled. Alterations of plasma lipid profiles by genetic manipulation in mice indeed strongly...
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