Article
Association between chronic disseminated candidiasis in adult acute leukemia and common IL4 promoter haplotypes.
The Journal of infectious diseases - 1 Apr 2003
Choi Eun Hwa, Foster Charles B, Taylor James G, Erichsen Hans Christian, Chen Renee A, Walsh Thomas J, Anttila Veli-Jukka, Ruutu Tapani, Palotie Aarno, Chanock Stephen J
Abstract excerpt
Chronic disseminated candidiasis (CDC) is a form of Candida species infection observed primarily in patients with acute leukemia. To investigate possible genetic factors associated with CDC, we conducted a pilot study of 40 patients with both leukemia and CDC and 50 control patients with leukemia only. A common haplotype of the IL4 promoter (-1098T/-589C/-33C) was overrepresented in patients with CDC (P= .01;...
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