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Article

Deletion of alpha‐synuclein decreases impulsivity in mice

10 Dec 2011

Abstract excerpt

The presynaptic protein alpha-synuclein, associated with Parkinson's Disease (PD), plays a role in dopaminergic neurotransmission and is implicated in impulse control disorders (ICDs) such as drug addiction. In this study we investigated a potential causal relationship between alpha-synuclein and impulsivity, by evaluating differences in motor impulsivity in the 5-choice serial reaction time task (5-CSRTT) in...

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PMID: 22142176
DOI: 10.1111/j.1601-183x.2011.00758.x

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