Article
Brain-Derived neurotrophic factor Val66Met induces female-specific changes in impulsive behaviour and alcohol self-administration in mice.
Behavioural brain research - 5 Mar 2021
Hogan Natasha L, Jaehne Emily J, Bak Sharon, Djouma Elvan, van den Buuse Maarten
Abstract excerpt
Substance use disorders are a debilitating neuropsychiatric condition, however it remains unclear why some individuals are at greater risk of substance use disorders than others and what genetic factors determine such individual differences. Impulsivity appears a promising candidate endophenotype to bridge the gap between genetic risk and addiction. Brain-derived neurotrophic factor (BDNF), and in particular the...
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