A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation.

doi:10.1136/jmedgenet-2011-100174

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Article

A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation.

Journal of medical genetics - 1 Jan 2012

Dalgaard Marlene D, Weinhold Nils, Edsgärd Daniel, Silver Jeremy D, Pers Tune H, Nielsen John E, Jørgensen Niels, Juul Anders, Gerds Thomas A, Giwercman Aleksander, Giwercman Yvonne L, Cohn-Cedermark Gabriella, Virtanen Helena E, Toppari Jorma, Daugaard Gedske, Jensen Thomas S, Brunak Søren, Rajpert-De Meyts Ewa, Skakkebæk Niels E, Leffers Henrik, Gupta Ramneek

Abstract excerpt

BACKGROUND: Testicular dysgenesis syndrome (TDS) is a common disease that links testicular germ cell cancer, cryptorchidism and some cases of hypospadias and male infertility with impaired development of the testis. The incidence of these disorders has increased over the last few decades, and testicular cancer now affects 1% of the Danish and Norwegian male population. METHODS: To identify genetic variants that...

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Identifiers

PMID: 22140272
DOI: 10.1136/jmedgenet-2011-100174
PMCID: PMC3284313

Genes

TGFBR3
BMP7
KITLG

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Source receipt: pubmed, retrieved 6 Sept 2026.

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