Article
The involvement of integrin β1 signaling in the migration and myofibroblastic differentiation of skin fibroblasts on anisotropic collagen-containing nanofibers.
Biomaterials - 1 Feb 2012
Huang Chengyang, Fu Xiaoling, Liu Jie, Qi Yanmei, Li Shaohua, Wang Hongjun
Abstract excerpt
Utilization of nanofibrous matrices for skin wound repair holds great promise due to their morphological and dimensional similarity to native extracellular matrix (ECM). It becomes highly desired to understand how various nanofibrous matrices regulate skin cell behaviors and intracellular signaling pathways, important to tuning the functionality of tissue-engineered skin grafts and affecting the wound healing...
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