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Article

Carriers of lecithin cholesterol acyltransferase gene mutations have accelerated atherogenesis as assessed by carotid 3.0-T magnetic resonance imaging [corrected].

Journal of the American College of Cardiology - 6 Dec 2011

Duivenvoorden Raphaël, Holleboom Adriaan G, van den Bogaard Bas, Nederveen Aart J, de Groot Eric, Hutten Barbara A, Schimmel Alinda W, Hovingh G Kees, Kastelein John J P, Kuivenhoven Jan Albert, Stroes Erik S G

Abstract excerpt

OBJECTIVES: The aim of this study was to investigate the role of reduced lecithin: cholesterol acyltransferase (LCAT) function on atherogenesis using 3.0-T carotid magnetic resonance imaging (MRI) and B-mode ultrasound. BACKGROUND: The role of low high-density lipoprotein cholesterol as a causal factor in atherogenesis has recently been questioned. LCAT plays a key role in high-density lipoprotein cholesterol...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22133847
DOI: 10.1016/j.jacc.2010.11.092

Genes

LCAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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