Article
A genome-wide association study of renal cell carcinoma among African Americans.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2014
Purdue Mark P, Ye Yuanqing, Wang Zhaoming, Colt Joanne S, Schwartz Kendra L, Davis Faith G, Rothman Nathaniel, Chow Wong-Ho, Wu Xifeng, Chanock Stephen J
Abstract excerpt
Genome-wide association studies (GWAS) of renal cell carcinoma (RCC) in populations of European ancestry have identified four susceptibility loci. No GWAS has been conducted among African Americans (AA), who experience a higher incidence of RCC. We conducted a GWAS in which we analyzed 1,136,723 common single-nucleotide polymorphisms (SNP) among 255 cases and 375 controls of African ancestry, and further...
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