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Article

Minimal residual disease monitoring based on FLT3 internal tandem duplication in adult acute myeloid leukemia.

Leukemia research - 1 Mar 2012

Abdelhamid Emna, Preudhomme Claude, Helevaut Nathalie, Nibourel Olivier, Gardin Claude, Rousselot Philippe, Castaigne Sylvie, Gruson Bérengère, Berthon Céline, Soua Zohra, Renneville Aline

Abstract excerpt

FLT3 internal tandem duplication (FLT3-ITD) is usually considered as a bad marker for minimal residual disease (MRD) follow-up in acute myeloid leukemia (AML). Our objective was to evaluate the suitability of FLT3-ITD as a target for MRD detection by real-time quantitative PCR, in comparison with two other molecular MRD markers, NPM1 mutation and WT1 overexpression, in 20 adult AML patients treated in Acute...

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Source

Identifiers

PMID: 22129478
DOI: 10.1016/j.leukres.2011.11.002

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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