Article
Molecular measurable residual disease monitoring and transplant indications in NPM1 mutated acute myeloid leukemia.
Bone marrow transplantation - 1 Feb 2025
Christopher Mary R, Nawas Mariam T, Reagan John L
Abstract excerpt
NPM1 mutated acute myeloid leukemia (AML) comprises roughly 30% of all AML cases and is mainly classified as favorable or intermediate-risk according to the European Leukemia Net stratification. Some patients, however, either have a poor response to initial intensive chemotherapy or ultimately relapse. NPM1 mutations are common, generally stable at early relapse and AML specific, features which make them ideal...
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