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Article

Minimal residual disease based on patient specific Flt3-ITD and -ITT mutations in acute myeloid leukemia.

Leukemia research - 1 Jul 2005

Scholl Sebastian, Loncarevic Ivan F, Krause Claudia, Kunert Christa, Clement Joachim H, Höffken Klaus

Abstract excerpt

We present our first experiences with determination of minimal residual disease (MRD) based on patient specific Flt3-ITD (internal tandem duplication) mutations. We analysed MRD status of 11 AML patients in a retrospective investigation and its potential impact on the follow up of these patients. In five out of six patients with a positive Flt3-ITD based MRD status a relapse of AML was observed in the follow up...

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Identifiers

PMID: 15921740
DOI: 10.1016/j.leukres.2004.12.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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