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Article

Minimal residual disease detection in acute myeloid leukemia by mutant nucleophosmin (NPM1): comparison with WT1 gene expression.

Clinica chimica acta; international journal of clinical chemistry - 1 Sept 2008

Barragan Eva, Pajuelo Juan C, Ballester Sandra, Fuster Oscar, Cervera Jose, Moscardo Federico, Senent Leonor, Such Esperanza, Sanz Miguel A, Bolufer Pascual

Abstract excerpt

BACKGROUND: Molecular analysis of minimal residual disease is only applicable in acute myeloblastic leukemia (AML) patients with genetic markers (20-30%). This study analyzes the feasibility of the real-time quantitative polymerase chain reaction (RQ-PCR) assay to detect mutant nucleophosmin (NPM1) during follow-up in AML patients. Moreover, we compare the NPM1 results with those of WT1 expression to MRD...

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Source

Identifiers

PMID: 18590714
DOI: 10.1016/j.cca.2008.05.021

Genes

NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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