Article
Monitoring of minimal residual disease in acute myeloid leukemia.
Cancer - 1 Jan 2008
Kern Wolfgang, Haferlach Claudia, Haferlach Torsten, Schnittger Susanne
Abstract excerpt
Two highly sensitive methods, multiparameter flow cytometry (MFC) and real-time quantitative PCR (RQ-PCR), are increasingly used to monitor minimal residual disease (MRD) and to guide risk-adapted management in acute myeloid leukemia (AML). An independent prognostic impact has been demonstrated for MRD levels obtained by both methods. MFC has been found particularly useful for assessment of early clearance of...
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