Article
Analyses of minimal residual disease based on Flt3 mutations in allogeneic peripheral blood stem cell transplantation.
Journal of cancer research and clinical oncology - 1 May 2005
Scholl Sebastian, Loncarevic Ivan F, Krause Claudia, Clement Joachim H, Höffken Klaus, Sayer Herbert G
Abstract excerpt
PURPOSE: Activating Flt3 mutations are observed in about 30% of patients with acute myeloid leukaemia (AML) and individual Flt3 mutations are applicable for minimal residual disease (MRD) analyses. METHODS: We investigated the MRD status in four AML patients carrying different Flt3 mutations (three patients with Flt3 length mutations of the juxtamembrane domain, one patient carrying a mutation of the Flt3...
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