Article
Suppressor of cytokine signaling 4 detected as a novel gastric cancer suppressor gene using double combination array analysis.
World journal of surgery - 1 Feb 2012
Kobayashi Daisuke, Nomoto Shuji, Kodera Yasuhiro, Fujiwara Michitaka, Koike Masahiko, Nakayama Goro, Ohashi Norifumi, Nakao Akimasa
Abstract excerpt
BACKGROUND: Molecular mechanisms behind the oncogenesis of gastric cancer (GC) have yet to be identified. METHODS: A novel candidate tumor-suppressor gene, which is also associated with inhibition of epidermal growth factor (EGF), was sought by means of double combination array analysis for use as a prognostic marker of GC. This consisted of expression array and single nucleotide polymorphism array analysis,...
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