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Article

Inactivation of the H-2Klk gene could involve the substitutions of methylated CpGs.

Journal of immunogenetics - 1 Jan 2000

Sim B C, Grosveld F G, Hui K M

Abstract excerpt

By the isolation of overlapping cosmid clones and 'chromosome walking' studies from the H-2Kk gene, we have obtained cosmid clones encoding the H-2Klk gene from two separate cosmid libraries. The nucleotide sequence of one of the clones was determined. The cloned H-2Klk gene could be transcribed in vitro to give a normal H-2 class I mRNA of 1.7 kb. However, the deletion of four nucleotides in exon 3 of the H-2Klk...

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Identifiers

PMID: 2212699
DOI: 10.1111/j.1744-313x.1990.tb00866.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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