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Article

Toward the establishment of a prediction system for the personalized treatment of chronic hepatitis C.

The Journal of infectious diseases - 15 Jan 2012

Ochi Hidenori, Hayes C Nelson, Abe Hiromi, Hayashida Yasufumi, Uchiyama Tomotaka, Kamatani Naoyuki, Nakamura Yusuke, Chayama Kazuaki

Abstract excerpt

BACKGROUND: Although several direct-acting antivirals (DAAs) are now available, the therapy regimen for chronic hepatitis C will continue to include pegylated interferon and ribavirin for the foreseeable future. Despite their improved rate of sustained virological response (SVR), DAAs pose increased risks of side effects and selection for antiviral resistance. Not all patients require DAA to achieve SVR, whereas...

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PMID: 22124128
DOI: 10.1093/infdis/jir726

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