Article
A machine learning-based treatment prediction model using whole genome variants of hepatitis C virus.
PloS one - 1 Jan 2020
Haga Hiroaki, Sato Hidenori, Koseki Ayumi, Saito Takafumi, Okumoto Kazuo, Hoshikawa Kyoko, Katsumi Tomohiro, Mizuno Kei, Nishina Taketo, Ueno Yoshiyuki
Abstract excerpt
In recent years, the development of diagnostics using artificial intelligence (AI) has been remarkable. AI algorithms can go beyond human reasoning and build diagnostic models from a number of complex combinations. Using next-generation sequencing technology, we identified hepatitis C virus (HCV) variants resistant to directing-acting antivirals (DAA) by whole genome sequencing of full-length HCV genomes, and...
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