Article
Pretreatment prediction of response to peginterferon plus ribavirin therapy in genotype 1 chronic hepatitis C using data mining analysis.
Journal of gastroenterology - 1 Mar 2011
Kurosaki Masayuki, Sakamoto Naoya, Iwasaki Manabu, Sakamoto Minoru, Suzuki Yoshiyuki, Hiramatsu Naoki, Sugauchi Fuminaka, Yatsuhashi Hiroshi, Izumi Namiki
Abstract excerpt
BACKGROUND: This study aimed to develop a model for the pre-treatment prediction of sustained virological response (SVR) to peg-interferon plus ribavirin therapy in chronic hepatitis C. METHODS: Data from 800 genotype 1b chronic hepatitis C patients with high viral load (>100,000 IU/ml) treated by peg-interferon plus ribavirin at 6 hospitals in Japan were randomly assigned to a model building (n = 506) or an...
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