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Article

Genetic predisposition of responsiveness to therapy for chronic hepatitis C.

Pharmacogenomics - 1 Jul 2006

Hwang Yuchi, Chen Ellson Y, Gu Z John, Chuang Wan-Long, Yu Ming-Lung, Lai Ming-Yang, Chao You-Chen, Lee Chuan-Mo, Wang Jing-Houng, Dai Chia-Yen, Shian-Jy Bey Monica, Liao Ya-Tang, Chen Pei-Jer, Chen Ding-Shinn

Abstract excerpt

BACKGROUND: A combination of interferon-alpha (IFN-alpha) and ribavirin has been the choice for treating chronic hepatitis C (CHC) patients. It achieves an overall sustained response rate of approximately 50%; however, the treatment takes 6-12 months and often brings significant adverse reactions to some patients. It would therefore be beneficial to include a pretreatment evaluation in order to maximize the...

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Source

Identifiers

PMID: 16886895
DOI: 10.2217/14622416.7.5.697

Genes

ADAR
CASP5
FGF1
IFI44
TAP2
TGFBRAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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