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Article

Individualized therapy for hepatitis C infection: focus on the interleukin-28B polymorphism in directing therapy.

Molecular diagnosis & therapy - 1 Feb 2014

Lee Tzu-Hao, Tillmann Hans L, Patel Keyur

Abstract excerpt

Hepatitis C virus—a major global cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma—affects millions of people worldwide. Pegylated interferon (Peg-IFN) and ribavirin (RBV) had been the standard treatment for a decade until availability of the protease inhibitors in 2011. However, current antiviral therapy is still IFN-based and is associated with significant side effects and variable treatment...

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PMID: 24022240
DOI: 10.1007/s40291-013-0053-4

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ITPA

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