Article
Epigenetic discordance at imprinting control regions in twins.
Epigenomics - 1 Jun 2011
Ollikainen Miina, Craig Jeffrey M
Abstract excerpt
Imprinting control regions are differentially methylated in a parent-of-origin-dependent manner and this methylation state is inherited through the germline. These regions control parent-specific monoallelic expression of their target genes. Genetically identical organisms show considerable variation in their epigenomes owing to environmental and stochastic influences creating fluctuations in phenotype....
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